TORONTO  — Tom Hanks, Halle Berry and their cast mates have put in some serious overtime on their genre-bending film “Cloud Atlas.”

Members of the large ensemble of actors take on multiple roles in the epic tale that premiered Saturday night at the Toronto International Film Festival.

Hanks, Berry and their co-stars play as many as half a dozen different characters in “Cloud Atlas,” whose action stretches across centuries from the mid-1800s to the distant future.

Berry’s roles include a journalist uncovering a nuclear power conspiracy to an elderly composer’s adulterous wife to a woman leading the remnants of earth-bound humanity to a new home.