INDIANAPOLIS  — Peyton Manning and the Indianapolis Colts ended their successful partnership with a tearful goodbye Wednesday, when team owner Jim Irsay released the star quarterback rather than pay a whopping $28 million bonus while there are lingering questions about his health.

“We all know that nothing lasts forever,” Manning said. “Times change, circumstances change, and that’s the reality of playing in the NFL.”

Manning and Irsay each paused frequently, fighting tears and their voices shaking, as they appeared together at a news conference at the Colts’ team complex.